P2RY4 and neoplasm: Analysis of publicly available human PDAC scRNA-seq data21 revealed that P2RY2 was weakly expressed in tumor epithelial cells and ECs, P2RY4 was not detectable, P2RY6 was strongly expressed in macrophages and ECs, and P2YR14 expression was restricted to fibroblasts, T and B cells and a small subset of macrophages (Fig. 6a).