Available studies have shown that Mir22hg plays a cancer inhibitory role in gastric cancer (Li and Wang 2019), hepatocellular carcinoma (Su et al. 2018), lung cancer (Wang et al. 2023a, b), and colorectal cancer (Xu et al. 2020), whereas it promotes tumor progression in esophageal cancer (Su et al. 2019). The gene discussed is MIR22HG; the disease is colorectal cancer.