NLRP3 and infection: Furthermore, in Schistosoma mansoni experimental infection as well as DCs in vitro exposed to Schistosoma egg antigen (SEA), the activation of several inflammasomes (NLRP3, NLRP6, and AIM2) has been documented [14, 15], and liver pathology elicited by this fluke is largely attributed to NLRP3 inflammasome activation [16, 17].