While angiogenic defects have been reported in the mdx mice as well as in golden retrieval muscular dystrophy (GRMD; canine model of DMD) (Verma et al., 2010; Latroche et al., 2015; Verma et al., 2019; Kodippili et al., 2021; Podkalicka et al., 2021), it is not clear whether VEGF family and its receptors are implicated in human dystrophinopathies. The gene discussed is VEGFA; the disease is neuromuscular disease caused by qualitative or quantitative defects of dystrophin.