Therefore, we crossed the MuSC-Flt1Δ/Δ mice with the chronically regenerating DMD model mice (mdx) to generate mdx:MuSC-Flt1Δ/Δ mice, and analyzed long-term effects of Flt1 deletion (Figure 4A, Figure 4—figure supplement 1B and C). Here, FLT1 is linked to Duchenne muscular dystrophy.