CD8A and diffuse large B-cell lymphoma: To validate the prognostic role of glycolytic biomarkers and IFN_TAM at the spatial transcriptomic level, as well as the relationship between glycolytic levels, IFN_TAM, and CD8+ T cell infiltration, spatial transcriptomic analysis was performed on tissue samples from 10 patients with DLBCL before R-CHOP treatment.