POU5F1 and hepatocellular carcinoma: Among these signatures, IL6 [47, 48], IGF1R [48, 49], NANOG [50], NCF1 [5], POU5F1 [52], TERT [53], SHH [54], CCR1 [55], SRC [56] and CXCL11 [57] have been reported to have clinical associations with the risk of HCC recurrence.