TP53 and B-cell chronic lymphocytic leukemia: On the research EHR, on a set of patients separate from those that CLL-TIM was trained on, CLL-TIM achieved Matthew’s correlation coefficient (MCC) of 0.56 (95% CI: 0.42–0.70) (n = 145) on the subset of patients with no missing CLL-IPI variables (Binet Staging, IGHV mutational status, β2 microglobulin, del17p/TP53 mutation) and on which CLL-TIM showed high-confidence in its prediction10.