Several studies including ours have demonstrated the pro-tumorigenic role of OSM and its receptor OSMR in solid tumors such as breast cancer5,6, pancreatic cancer7,8, endometrial cancer9, cervical cancer10 and ovarian cancer11 and their contribution to cancer aggressiveness and metastasis, cancer stemness, epithelial to mesenchymal transition (EMT)8,12, inflammatory response13, and angiogenesis14. This evidence concerns the gene OSM and cancer.