VIM and cancer: As expected, we observed that the stable overexpression of OSMR increased the expression of EMT-associated genes (N-cadherin and vimentin) and cancer stemness-associated genes (CD44, SNAIL, and c-Kit) in both A2780 and OVCAR8 cells (Fig. 2e, f); whereas OSMR upregulation decreased the levels of CD24 and E-cadherin which are required for non-tumorigenic epithelial characteristics.