However, the study has several limitations: (1) cats with feline hemotropic mycoplasmosis were not histopathologically examined for glycocalyx damage, (2) the patient population included in the study was small, and (3) heparanase and heparan sulfate concentrations could not be measured in the present study because cat-specific commercial ELISA kits were not available. The gene discussed is HPSE; the disease is Mycoplasmoides infection.