SLC17A8 and deafness: During previous studies, the complete lack of VGluT3 resulted in deafness (Seal et al., 2008), highly anxious behavior phenotype (Amilhon et al., 2010; Balazsfi et al., 2016; Sakae et al., 2019), altered fear, and stress reactivity (Horvath et al., 2018; Balazsfi et al., 2018a).