ITGAM and arthritic joint disease: To better understand how Dnmt3aR878H/+ leukocytes exacerbate experimental periodontitis and arthritis, we performed single-cell RNA sequencing (scRNA-seq) in sorted CD45.2+CD11b+, CD45.1+CD11b+, CD45.2+CD3+, and CD45.1+CD3+ cells from 10%Dnmt3aR878H/+BMT and control mice, which were subjected to 5-day LIP or 7-day CAIA 12 weeks post-BMT.