MAPT and Alzheimer disease: A meta‐analysis synthesized researches on the association between the personality and the risk of dementia and revealed that higher conscientiousness is associated with a lower risk of dementia.[31] Additionally, Terracciano et al.[32] examined the relationship between personality traits and amyloid and tau deposition, which are defining markers of AD neuropathology, and found that conscientiousness was a protective factor against AD key neuropathology.