THBS1 and renal fibrosis: Notably, while peptide‐mediated blocking of THBS1 decreased renal fibrosis by preventing TGF‐β activation, it did not affect mesangial cell proliferation, nor did it decrease monocyte/macrophage infiltration.[39] As THBS1 is known to promote both mesangial cell proliferation and monocyte recruitment, THBS1‐driven renal fibrosis likely involves mechanisms beyond the activation of latent TGF‐β.[43]