For participants without a history of HF, an incremental unit in DII was associated with a significant elevation in NT-proBNP levels across different models: an increase of 9.69 pg/mL in the crude model (95% confidence interval [CI]: 6.47, 12.91; p < 0.001), 8.57 pg/mL in Model I (95% CI: 4.97, 12.17; p < 0.001), and 5.54 pg/mL in Model II (95% CI: 1.75, 9.32; p = 0.001) with further adjustments. Here, NPPB is linked to hydrops fetalis.