Correspondingly, the APOB gene, which encodes the primary apolipoprotein for VLDL synthesis, was also dramatically decreased along with hepatic steatosis (13.4 times higher in the eCtrl group than eHS-II group, Padj < 0.05, β = 4,483.77, post hoc Wilcoxon rank-sum test, Fig. 3C). The gene discussed is APOB; the disease is fatty liver disease.