Although podocyte specific ABCA1 knockout mice did not show obvious renal injury, podocyte ABCA1 knockout in diabetic ob/ob mice led to higher proteinuria and worsened diabetic kidney injuries compared to wildtype diabetic ob/ob mice,36 demonstrating an essential role of ABCA1‐mediated cholesterol efflux in DKD podocytes. The gene discussed is ABCA1; the disease is diabetic kidney disease.