To comprehensively understand the effects of mutant proteins and elucidate potential pathological mechanisms of TFG p.(Lys59Asn), our functional studies included other representative pathogenic TFG variants: p.(Arg106Cys) and p.(Arg106His) linked to SPG57, and p.(Gly269Val) and p.(Pro285Leu) associated with CMT2 and HSMN‐P (Fig. 1C,D). Here, TFG is linked to motor peripheral neuropathy.