TOB1 and cancer: To check whether the transcriptional upregulation of the subunits of the TIM23 complex is specific in cancer, we extended our study by analyzing the transcript levels of the proteins that build other mitochondrial translocases or insertases, namely translocase of the outer membrane (TOM), mitochondrial sorting and assembly machinery (SAM, also known as TOB) and translocase of the inner membrane 22 (TIM22).