SNAI1 also known as ZEB2 (zinc finger E-box binding homeobox 2), as well as ZEB1, E2-2 (as also known as transcription factor 4) and Twist (Castilla et al. 2011), were all up-regulated in ECSs, similar to other tumor types (Wang and Zhou 2011; Peinado et al. 2007; Moreno-Bueno et al. 2008). This evidence concerns the gene ZEB2 and neoplasm.