PNMA1 and myeloid sarcoma: The inflammaging model had identified a series of inflammatory markers associated with neuronal formation in MS (Table 2): DO1 had a role in regulating neuronal excitability (Correale, 2021); SLC18A2 was neuroprotective and PNMA1 promoted neuronal apoptosis (Chen and D'Mello, 2010; Black et al., 2021).