These include MDS/MPN-SF3B1-T, which impressively demonstrates the intermediate position between MDS and MPN: MDS/MPN-SF3B1-T has a characteristic SF3B1 mutation similar to the MDS subtype MDS-SF3B1 and concurrently harbours JAK2 mutations as found in MPN [6]. The gene discussed is SF3B1; the disease is myeloproliferative disorder.