TNFRSF14 and aneurysmal bone cyst: The ABC subtype is characterized by gains of 3/3q, 18/18q21 (BCL2), 19q13 (SPIB), and losses of 6q23 (TNFAIP3) and 9p21 (CDKN2A/2B), and somatic variants affecting PIM1, MYD88L265P, and CD79B. The GCB subtype is defined by gains of 2p16/REL and 13q32/MIR17HG, trisomies of chromosomes 7 and 12, deletions of 1p36/TNFRSF14 and 10q23/PTEN, and somatic variants in TNFRSF14, SOCS1, EZH2[12].