Of importance, TET2 and DNMT3A mutations have been shown to arise in myeloid precursor cells and are classical components of the concept of clonal haematopoiesis, whereas IDH2 and RHOA formation has been shown to occur in somatic, T-cell – committed – tumour cells, thus linking clonal haematopoiesis with T-cell lymphomagenesis. This evidence concerns the gene TET2 and neoplasm.