The KEGG analysis showed that the key genes were mainly enriched in tumor and immune-related signaling pathways, such as the TNF signaling pathway, Viral carcinogenesis, p53 signaling pathway, Pancreatic cancer, RIG−I−like receptor signaling pathway, IL-17 signaling pathway, etc. (Figure 2B). Here, TP53 is linked to familial pancreatic carcinoma.