CCR7 and neoplasm: For example, in experiments where DCs are co-cultured with apoptotic tumor cells, the expression of CCR7 is induced to increase, which aids in the migration of DCs and thereby promotes the formation of anti-tumor immune responses (242, 243), However, in some cases, despite DCs phagocytosing apoptotic tumor cells, their antigen presentation to CD8+ T cells is suboptimal.