In addition, APS can also downregulate the protein expression of Bcl-2-associated X protein and cleaved Caspase3 and upregulate Bcl-2, antagonizing cell apoptosis and protecting peritoneal tissue, and it is confirmed that APS is associated with the expression level of proteins related to mitochondrial apoptosis of HMrSV5 (Zhao, Shan, et al., 2020). The gene discussed is BCL2; the disease is autoimmune polyendocrinopathy.