X-linked dystonia-parkinsonism (XDP, DYT/PARK-TAF1, OMIM #314250), the term first coined by Lee et al., in 1991 [1], refers to an adult-onset, severe, and frequently lethal neurodegenerative movement disorder found exclusively in individuals of Filipino origin. The gene discussed is TAF1; the disease is X-linked dystonia-parkinsonism.