Finally, genotyping 2,000 eczema patients and 15,000 controls with the Immunochip, a custom genotyping array that was specifically designed for studying chronic inflammatory, immune-related diseases and that included 200,000 common and rare variants from 186 candidate loci, identified low frequency variants in the docking protein 2 gene (DOK2) [26]. The gene discussed is DOK2; the disease is Eczematoid dermatitis.