Three distinct clinical phenotypes of neutrophil recovery have been observed after CAR T. The most common recovery pattern observed in a multicenter retrospective analysis was that of intermittent recovery in 52%, consisting of initial recovery with G-CSF stimulation for the neutropenia following lymphodepletion followed by a biphasic second reduction in absolute neutrophil count (ANC) in month two post-CAR T, and then with another recovery in the subsequent weeks. The gene discussed is CSF3; the disease is Decreased total neutrophil count.