ERFE and myelodysplastic syndrome: In that study, total serum ERFE levels were significantly higher in MDS patients and particularly in cases with SF3B1mut, where the increased serum ERFE levels included higher expression of the ERFEVPFQ variant (135.0 ± 72.5 ng/ml in the variant compared to 62.1 ± 36.7 ng/ml in the wild type).