NCF4 and B-cell non-Hodgkin lymphoma: Interestingly, in a previous study including an identification (n = 337) and a validation cohort (n = 572) of patients with aggressive B-cell NHL treated with doxorubicin-based chemotherapy, only the rs1883112 SNP in the NCF4 gene out of 53 candidate SNPs in 29 genes was successfully validated[68].