The role of MYBL2 in oxaliplatin resistance of CRC cells was studied and MYBL2 was shown to induce the expression of the lncRNA CCAT1, which led to upregulation of suppressor of cytokine signaling 3 (SOCS3) and resistance to oxaliplatin in vitro and in vivo[53]. Here, SOCS3 is linked to colorectal carcinoma.