Further cancers sensitive to MYB-targeted therapy include various leukemias (e.g., BCR/ABL-positive CML and ALL) and lymphomas (DLBCL, Burkitt lymphoma), gynecological cancers (ER-positive breast cancer, OC), gastrointestinal cancers, and CRPC. The gene discussed is MYB; the disease is chronic myelogenous leukemia, BCR-ABL1 positive.