MYBL2 regulates cell cycle, apoptosis, and epithelial-to-mesenchymal transition (EMT), and is overexpressed in leukemia and several solid tumors (e.g., breast, lung, colorectal and gallbladder cancer, hepatocellular and esophageal squamous cell carcinoma, glioma, and neuroblastoma)[22]. The gene discussed is MYBL2; the disease is central nervous system cancer.