AKT1 and non-small cell lung carcinoma: However, in ovarian cancer, it was demonstrated that the inhibition of the NF-κB (p65) pathway via resveratrol significantly increased the efficiency of TRAIL-induced apoptosis in NSCLC, while pro-survival effects by NF-κB, Akt, and ERK(1/2) and anti-apoptosis actions by Six1 inhibited the TRAIL-R1/TRAIL-R2 pathways[93,94].