Huang et al. screened 63 immune genes related to melanoma prognosis, sorted out a gene set with eight immune genes (PSME1, CDC42, CMTM6, HLA-DQB1, HLA-C, CXCR6, CD8B, TNFSF13) as melanoma prognostic markers, and verified their good accuracy as prognostic markers by using TCGA cohort[136]. This evidence concerns the gene HLA-C and melanoma.