KCNQ1OT1 and cancer: KCNQ1OT1 (KCNQ1 Opposite Strand/Antisense Transcript 1) is a lncRNA transcribed in the antisense direction to the KCNQ1 gene, in the chromosomal region 11p15.5 containing two clusters of imprinted genes; KCNQ1OT1 is exclusively expressed from the paternal allele, however it is abnormally expressed from both chromosomes in most patients with the imprinting disorder of Beckwith-Wiedemann syndrome, and in multiple types of cancers (https://www.genecards.org) [355].