BMI, body mass index; WC, waist circumference; WHR, waist hip ratio; SBP, systolic blood pressure; DBP, diastolic blood pressure; HbA1c, glycated hemoglobin; HOMA-IR, homeostasis model assessment insulin resistance; HDL-C, high-density lipoprotein; LDL-C, low-density lipoprotein; VLDL-C, very low-density lipoprotein; BUN, blood urea nitrogen; AST, aspartate transaminase; ALT, alanine transaminase; SFRP4, secreted frizzled-related protein 4; CPR, C-protein reactive; Il-6, interleukin 6; IL-1b, interleukin 1 beta; IL-8, interleukin 8; IL-10, interleukin 10. The gene discussed is CXCL8; the disease is Insulin resistance.