FOXO1 and syringocystadenoma papilliferum: miR-486-5p negatively regulated FOXO1, and the knockdown of FOXO1 reversed the effect of miR-486-5p in K. pneumonia-treated alveolar epithelial cells.<h4>Conclusion</h4>miR-486-5p acted as a biomarker for the screening and monitoring of SCAP and predicting the malignancy of MCAP.