RAB3B and non-small cell lung carcinoma: Dysregulation of Rab3B may be a consequence of LKB1 gene inactivation, as we found that LKB1-mutated NSCLC cell lines express higher levels of Rab3B than NSCLC cells carrying wild-type LKB1. Moreover, knockdown of LKB1 increases and re-expression of LKB1 suppresses Rab3B expression in NSCLC cells, suggesting the negative regulation of Rab3B by LKB1.