ACHE and myasthenia gravis: Reversible AChE inhibitors have proved useful in treating various neurological conditions, with inhibitors crossing the blood–brain barrier (BBB, for example, rivastigmine) used in the therapy of dementia in Alzheimer’s and Parkinson’s diseases42 and ones not crossing the BBB (for example, pyridostigmine) used in the therapy of myasthenia gravis.