IQGAP1 and acute myeloid leukemia: Future studies will focus on optimization of the structure of UR778Br followed by in vivo evaluation in xenografts of IQGAP1 expressing human AML cell lines as well as on engraftment and survival of primary AML samples in NOD.Cg-PrkdcscidIl2rgtm1Wjl (NSG) mice.