IL17A and psoriasis: For example, glucose transporter 1 (GLUT1) is elevated in psoriatic epidermis from the patient and imiquimod (IMQ) induced psoriasis mouse model, genetic and pharmacological Glut1 inactivation decreased hyperplasia in mouse models of psoriasis-like disease [7]; pyruvate kinase M2 contributes to psoriasis progression by promoting proliferation and mediating interleukin-17 signaling in keratinocytes [8, 9].