Additionally, a study conducted by Shiling Hu17 only revealed that three Salvianolic acids can inhibit the entry of 2019-nCoV spike pseudovirus into ACE2 high expression cells by binding to the RBD of the 2019-nCoV spike protein and ACE2 protein, which prompted us to explore the potential of Danshen's ingredients treating COVID-19 in a comprehensive and systemic way. This evidence concerns the gene ACE2 and COVID-19.