INS and Glucose intolerance: 24 To our knowledge, only one published study has investigated the effects of DP on glucose homeostasis; Peshdary et al. reported that 28-day exposure of male mice to daily low-dose DP increased random-fed plasma insulin levels in chow-fed mice and exacerbated glucose intolerance in high-fat diet (HFD)-fed mice.25 These data suggest that much like brominated flame retardants, DP may also act as an endocrine disruptor, possibly via dysregulated insulin secretion.