TPX2 and esophageal cancer: Similarly, based on the analysis of 250 cases of esophageal tumor and paracarcinoma tissue, Sui et al. (Sui et al. 2019) showed that the TPX2 level was markedly enhanced in tumor tissues and was unfavorable for the 5-year OS of patients, which was proposed as an important indicator to assess prognosis in esophageal cancer.