Among these cancer types, high TPX2 expression may be a risk factor for poor prognosis in most cancers, such as adrenocortical cancer (ACC, HR = 2.27, p = 8.6e-7), kidney renal papillary cell carcinoma (HR = 2.08, p = 7.7e-13), and HCC (HR = 1.41, p = 7.4e-8). Here, TPX2 is linked to adrenal cortex carcinoma.