Our data also confirmed the previously described role of rs10757278, a risk SNP for CAD (Tcheandjieu et al. 2022) and MI (Helgadottir et al. 2007a), as being a putative causal variant of this risk haplotype block, which impairs binding of the IFNG responsive signal transducer STAT1 (Harismendy et al. 2011). Here, STAT1 is linked to coronary artery disorder.