MKI67 and psoriasis: In addition, the expression of ki67 and K6 was significantly elevated in the skin lesion tissues of the model group compared with the control group, and the expression of ki67 and K6 was significantly suppressed by the TAN-treated group compared with the model group (P < 0.05, Fig. 2F-G), suggesting that TAN could significantly alleviate the severity of psoriasis in mice.