TLR7 and psoriasis: IMQ is a Toll-like receptor (TLR7/8) agonist, which can induce inflammatory responses in mice, and its induced psoriasis-like model lesions in mice are characterized by increased epidermal hyperplasia, differentiation abnormalities, etc., and skin inflammation basically consistent with the pathological changes of psoriasis (Li et al. 2021; Silva-Abreu et al. 2023).