Our findings indicated that increasing age (OR = 1.085, 95%CI: 1.053–1.117, p < 0.001), high number of radiation treatments (OR = 1.103, 95%CI: 1.074–1.132, p < 0.001), low BMI (OR = 0.700, 95%CI: 0.618–0.793, p < 0.001), and low albumin levels (OR = 0.852, 95%CI: 0.789–0.921, p < 0.001) are significant nutritional risk factors in patients with nasopharyngeal carcinoma. This evidence concerns the gene ALB and nasopharyngeal carcinoma.