TP53 and cancer: KEGG enrichment analysis showed that a total of 41 KEGG pathways were significantly enriched (P < 0.05) (Table S5), and these DEGs were mainly implicated in p53 signaling pathway (ssc04115 and P = 0.0005), chronic myeloid leukemia (ssc05220 and P = 0.0006), proteoglycans in cancer (ssc05205 and P = 0.0007), fatty acid metabolism (ssc01212 and P = 0.0139), and MAPK signaling pathway (ssc04010 and P = 0.0142).