In our findings, comparing the HF group and the C group, we observed, in immunostaining for Bax and Bcl-2, a significant increase in Bax levels and the Bax/Bcl-2 ratio in the HF group and a decrease in Bcl-2 in the same group, indicating a possible activation of the apoptotic pathway in these animals. Here, BAX is linked to hydrops fetalis.