Using the top eight upregulated genes (SLPI, PLA2G2A, CXCL1, CCL20, REG1A, CLDN7, PI3, LGALS3) as a representative gene set for the high metabolic subcluster, we calculated the GSVA score of this gene set for each patient in the TCGA gastric cancer cohort. This evidence concerns the gene REG1A and gastric cancer.