HAVCR1 and breast carcinoma: Cai et al. (2021) developed a high-powered predictive classifier for the diagnosis of breast cancer via eight mRNAs from plasma extracellular vesicles (including TIM-1), which could provide a new approach for the early diagnosis of breast cancer. The study also showed that the relevance of interrogating the levels of TIM-1 protein as a diagnostic/prognostic biomarker of high-prevalence breast and lung cancers by using an amperometric disposable magnetic microparticles-assisted immunoplatform (Quinchia et al., 2024).